A joint research paper (Science Advances, 2023) with Dr. Yokoi from Nagoya University has been press-released by Tokyo Institute of Technology, Nagoya University, Hokkaido University, National Cancer Center, Keio University, Tokyo Medical University, and JST

We have developed a novel exosome capture method using polyketone chain-modified nanowires.

Dr. Yokoi from Nagoya University, School of Medicine, Dr. Ukai (formerly at Toyota Memorial Hospital), Prof. Kajiyama from Nagoya University, Graduate School of Medicine, Prof. Inokuma from Hokkaido University, Dr. Matsuzaki from Keio University, Dr. Yamamoto from the National Cancer Center Research Institute, and Prof. Ochiya from Tokyo Medical University, have successfully identified specific membrane proteins in ovarian cancer exosomes through comprehensive proteomic analysis.  We have also developed polyketone chain-modified nanowires as exosome separation materials.  This breakthrough is expected to serve as a valuable biomarker for ovarian cancer diagnosis and treatment prediction.

Identifying high-grade serous ovarian carcinoma-specific extracellular vesicles by polyketone-coated nanowires. Sci. Adv., 9, eade6958 (2023), 10.1126/sciadv.ade6958.